Synthesis and Crystal Structure of 4-(2-Methylene-1-ethyl-3,3-dimethylindoline-2’-yl)- 6,8-dibromo-1’-ethyl-3’,3’-dimethylspiro[3,4-dihydro-2H-1-benzopyran-2,2’-indoline]
金丹;张峰;张德纯
皖南医学院
Synthesis and Crystal Structure of 4-(2-Methylene-1-ethyl-3,3-dimethylindoline-2’-yl)- 6,8-dibromo-1’-ethyl-3’,3’-dimethylspiro[3,4-dihydro-2H-1-benzopyran-2,2’-indoline]
JIN Dana ; ZHANG Feng ; ZHANG De-Chun
Department of Pharmacy, Wannan Medical College, Wuhu 241002, China)Suzhou Yian Biotech Co., Ltd., Suzhou 215122, China
The title compound of 4-(2-methylene-1-ethyl-3,3-dimethylindoline-2-yl)-6,8-dibromo-1- ethyl-3,3-dimethylspiro[3,4-dihydro-2H-1-benzopyran-2,2-indoline], C33H36Br2N2O, as a dicondensed spiropyran (DC) has been synthesized by indoline in ethanol with 3,5-dibromo- salicyaldehyde. The compound was characterized by elemental analysis and IR spectra. Meanwhile, the crystal of the compound was obtained and determined by X-ray single-crystal diffraction. Crystal data: monoclinic system, space group P21/n, a = 12.9699(15), b = 12.5196(13), c = 19.327(2), β = 106.493(3)°, Mr= 636.46, V = 3009.1(6)3, Z = 4, F(000) = 1304, Dc= 1.405 g/cm3, μ = 2.722 mm-1, R = 0.0554 and wR = 0.1176 for 6892 independent reflections (Rint = 0.0354) and 5699 observed reflections (I > 2σ(I)).
The title compound of 4-(2-methylene-1-ethyl-3,3-dimethylindoline-2-yl)-6,8-dibromo-1- ethyl-3-dimethylspiro[3,4-dihydro-2H-1-benzopyran-2,2-indoline], C33H36Br2N2O, as a dicondensed spiropyran (DC) has been synthesized by indoline in ethanol with 3,5-dibromo- salicyaldehyde. The compound was characterized by elemental analysis and IR spectra. Meanwhile, the crystal of the compound was obtained and determined by X-ray single-crystal diffraction. Crystal data: monoclinic system, space group P21/n, a = 12.9699(15), b = 12.5196(13), c = 19.327(2), β = 106.493(3)°, Mr= 636.46, V = 3009.1(6)3, Z = 4, F(000) = 1304, Dc= 1.405 g/cm3, μ = 2.722 mm-1, R = 0.0554 and wR = 0.1176 for 6892 independent reflections (Rint = 0.0354) and 5699 observed reflections (I > 2σ(I)).
2010, Vol. 1 
